Episode 21: The Neuroscience of Gratitude: Feel It, Don’t Just List It – Entrée

entrees Nov 24, 2025

Download the 1-1-1 Gratitude Practice!

Most of us were taught to “be grateful.” But if you’ve ever written a gratitude list and felt nothing, you’re not alone—and you’re not doing it wrong. You’re just missing the part that actually changes the brain.

In this special Thanksgiving-week episode of Relish, Alyssia Sheikh dives into the real neuroscience of gratitude: how taking 10–20 seconds to actually feel a good moment is what rewires your emotional patterns, shifts the negativity bias, and signals safety to your nervous system. This isn’t a bypass, and it’s not about pretending everything is fine. It’s about giving your brain a chance to register what is good too.

You’ll learn why gratitude activates parasympathetic pathways (“rest-and-receive”), boosts dopamine and serotonin, supports immunity and sleep, and helps you show up to the holidays grounded and intentional. Alyssia also shares a 90-second guided practice, a beautifully simple 1–1–1 daily gratitude ritual, and practical ways to pair gratitude with boundaries—so you can bring presence into real life, not just onto paper.

In this episode, you’ll learn:

  • Why gratitude is a state of being, not a list
  • How 10–20 seconds of “staying with it” rewires your brain (experience-dependent neuroplasticity)
  • The science behind why gratitude softens the negativity bias
  • How to practice gratitude without minimizing your real feelings
  • A 90-second guided embodiment practice
  • A 1–1–1 Gratitude & Appreciation ritual you can use with partners, kids, or at the holiday table
  • How gratitude + boundaries help you navigate challenging family dynamics

💭 Reflection:
What’s one tiny moment in the past 24 hours that brought you ease, warmth, or connection? And what happens when you let your nervous system stay with that for just a few seconds longer?

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📘 Books Referenced

  • Hanson, R. & Mendius, R. (2009). Buddha’s Brain: The Practical Neuroscience of Happiness, Love & Wisdom
    (A central text explaining Hebbian learning, “neurons that fire together wire together,” and how to transform states into traits.) https://a.co/d/1p25W6l (include amazon affiliate link)

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